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COVID-19 Vaccines for People Who Are Moderately or Severely Immunocompromised


COVID-19 Vaccines: 2023-2024 Updated, Bivalent, and Original

2023–2024 updated COVID-19 vaccines

As of October 3, 2023, the 2023-2024 updated Novavax vaccine was recommended by CDC for use in the United States.

As of September 12, 2023, the 2023–2024 updated Pfizer-BioNTech and Moderna COVID-19 vaccines were recommended by CDC for use in the United States.

The 2023–2024 updated COVID-19 vaccines more closely target the XBB lineage of the Omicron variant. We anticipate the updated vaccines will be better at fighting currently circulating variants.

2022–2023 Bivalent vaccines

As of September 11, 2023, the bivalent Pfizer-BioNTech and Moderna COVID-19 vaccines are no longer available for use in the United States.

The 2022–2023 bivalent vaccines were designed to protect against both the original virus that causes COVID-19 and the Omicron variants BA.4 and BA.5. Two COVID-19 vaccine manufacturers, Pfizer-BioNTech and Moderna, had developed bivalent COVID-19 vaccines.

Original vaccines

As of April 18, 2023, the original Pfizer-BioNTech and Moderna COVID-19 vaccines are no longer available for use in the United States.

As of May 6, 2023, J&J/Janssen COVID-19 vaccine is no longer available for use in the United States.

Previous COVID-19 vaccines were called “original” because they were designed to protect against the original virus that causes COVID-19.



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